Selected Publications

Giesecke A, Johnstone PS, Lamaze A, Landskron J, Atay E, Chen KF, Wolf E, Top D., Stanewsky R. ( ): "A novel period mutation implicating nuclear export in temperature compensation of the Drosophila circadian clock " Current Biology (22), 01911-X | Abstract | Full Article
Thakkar N., Giesecke A, Bazalova O, Martinek J, Smykal V, Stanewsky R, Dolezel D ( ): "Evolution of casein kinase 1 and functional analysis of new doubletime mutants in Drosophila" Frontiers in Physiology 3 1062632 | Abstract | Full Article
Lorber C., Leleux S., Stanewsky R., Lamaze A. ( ): "Light triggers a network switch between circadian morning and evening oscillators controlling behaviour during daily temperature cycles " PLoS Genetics 18 (11), e1010487 | Abstract | Full Article
Johnstone Peter S , Ogueta M., Akay O., Top I., Syed S. , Stanewsky R., Top D. ( ): "Real time, in vivo measurement of neuronal and peripheral clocks in Drosophila melanogaster" eLife 11 e77029 | Abstract | Full Article
Lamaze A., Chen C, Leleux S., Xu M., George R., Stanewsky R. ( ): "A natural timeless polymorphism allowing circadian clock synchronization in "white nights" " Nature communications 13 (1724), | Abstract | Full Article
Eick AK., Ogueta M., Buhl E., Hodge JJL., Stanewsky R. ( ): "The opposing chloride cotransporters KCC and NKCC control locomotor activity in constant light and during long days" Current Biology 32 (6), 1420-1428.e4 | Abstract | Full Article
Klemz S., Wallach T., Korge S., Rosing M., Klemz R., Maier B., Fiorenza NC., Kaymak I., Fritzsche AK., Herzog ED., Stanewsky R., Kramer A. ( ): "Protein phosphatase 4 controls circadian clock dynamics by modulating CLOCK/BMAL1 activity" Genes & Development 35 1161-1174 | Abstract | Full Article
George R., Stanewsky R. ( ): "Peripheral Sensory Organs Contribute to Temperature Synchronization of the Circadian Clock in Drosophila melanogaster" Frontiers in Physiology 12 (622545), | Abstract | Full Article
Versteven M, Ernst KM, Stanewsky R ( ): "A Robust and Self-Sustained Peripheral Circadian Oscillator Reveals Differences in Temperature Compensation Properties with Central Brain Clocks" iScience 23 (8), 101388 | Abstract | Full Article
Ogueta M., Hardie RC, Stanewsky R. ( ): "Light Sampling via Throttled Visual Phototransduction Robustly Synchronizes the Drosophila Circadian Clock " Current Biology 30 (10), 2551-2563 | Abstract | Full Article
Fustin JM, Ye S, Rakers C, Kaneko K, Fukumoto K, Yamano M, Versteven M, Grünewald E, Cargill SJ, Tamai TK, Xu Y, Jabbur ML, Kojima R, Lamberti ML, Yoshioka-Kobayashi K, Whitmore D, Tammam S, Howell PL, Kageyama R, Matsuo T, Stanewsky R, Golombek DA, Johnson CH, Kakeya H, van Ooijen G, Okamura H ( ): "Methylation deficiency disrupts biological rhythms from bacteria to humans" Commun. Biol. 3 (1), 211 | Abstract | Full Article
Lamaze A., Stanewsky R. ( ): "DN1p or the “Fluffy” Cerberus of Clock Outputs" Frontiers in Physiology 10 1540 | Abstract | Full Article
Singh, S, Giesecke, A, Damulewicz, M, Fexova, S, Mazzotta, G M, Stanewsky, , Dolezel, D ( ): "New Drosophila Circadian Clock Mutants Affecting Temperature Compensation Induced by Targeted Mutagenesis of Timeless" Frontiers in Physiology 10 1442 | Abstract | Full Article
Roessingh S, Rosing M., Marunova M., Ogueta M., George R., Lamaze A., Stanewsky R. ( ): "Temperature synchronization of the Drosophila circadian clock protein PERIOD is controlled by the TRPA channel PYREXIA" Commun. Biol. 2 (246), | Abstract | Full Article
Zhao J., Warman GR., Stanewsky R., Cheeseman JF. ( ): "Development of the Molecular Circadian Clock and Its Light Sensitivity in Drosophila Melanogaster" J Biol Rhythms 34 (3), 272-282 | Abstract | Full Article
Ogueta M, Hardie RC, Stanewsky R ( ): "Non-canonical Phototransduction Mediates Synchronization of the Drosophila melanogaster Circadian Clock and Retinal Light Responses." Current Biology 28 (11), 1725-1735 | Abstract | Full Article
Chen C, Xu M, Anantaprakorn Y, Rossing M, Stanewsky R ( ): "nocte Is Required for Integrating Light and Temperature Inputs in Circadian Clock Neurons of Drosophila." Current Biology 28 (10), 1595-1605 | Abstract | Full Article
Roessingh S, Stanewsky R ( ): "The Drosophila TRPA1 Channel and Neuronal Circuits Controlling Rhythmic Behaviours and Sleep in Response to Environmental Temperature." Interntional Journal of Molecular Sciences 18 (10), 2028 | Abstract | Full Article
Harper REF, Ogueta M, Dayan P, Stanewsky R, Albert JT ( ): "Light Dominates Peripheral Circadian Oscillations in Drosophila melanogaster During Sensory Conflict." Journal of Biological Rhythms | Abstract | Full Article
Kistenpfennig C, Grebler R, Ogueta M, Hermann-Luibl C, Schlichting M, Stanewsky R, Senthilan PR, Helfrich-Förster C ( ): "A New Rhodopsin Influences Light-dependent Daily Activity Patterns of Fruit Flies." Journal of Biological Rhythms | Abstract | Full Article
Tang X, Roessingh S, Hayley Sean E , Chu ML , Tanaka NK, Wolfgang W, Seongho S , Stanewsky R, Hamada FN ( ): "The role of PDF neurons in setting preferred temperature before dawn in Drosophila" eLife 6:e23206 | Abstract | Full Article
Klemz R., Reischl S., Wallach T., Witte N., Jürchott K., Klemz S., Lang V., Lorenzen S., Knauer N., Heidenreich S., Xu M., Ripperger J. A., Schupp M., Stanewsky R., Kramer A. ( ): "Reciprocal regulation of carbon monoxide metabolism and the circadian clock" Nature Structural & Molecular Biology 24 (1), 15–22 | Abstract | Full Article
Harper REF, Dayan P, Albert JT, Stanewsky R ( ): "Sensory Conflict Disrupts Activity of the Drosophila Circadian Network" Cell Reports 17 (7), 1711–1718 | Abstract | Full Article
Buhl E, Bradlaugh A, Ogueta M, Chen KF, Stanewsky R, Hodge JJ ( ): "Quasimodo mediates daily and acute light effects on Drosophila clock neuron excitability " PNAS 113 (47), 13486–13491 | Abstract | Full Article
Roessingh S, Wolfgang W, Stanewsky R ( ): "Loss of Drosophila melanogaster TRPA1 Function Affects “Siesta” Behavior but Not Synchronization to Temperature Cycles" Journal of Biological Rhythms 30 (6), 492-505 | Abstract | Full Article
Chen C, Buhl E, Xu M, Croset V, S. Rees J, Lilley KS, Benton R, Hodge JJ, Stanewsky R ( ): "Drosophila Ionotropic Receptor 25a mediates circadian clock resetting by temperature" Nature 527 (7579), 516-520 | Abstract | Full Article
Simoni A, Wolfgang W, Topping MP, Kavlie RG, Stanewsky R, Albert JT ( ): "A mechanosensory pathway to the Drosophila circadian clock" Science 343 (6170), 525-528 | Abstract | Full Article
Wolfgang W, Simoni A, Gentile C, Stanewsky R ( ): "The Pyrexia receptor potential channel mediates circadian clock synchronization to low temperature cycles in Drosophila melanogaster." Proc Biol Scie 280 (1768), | Abstract | Full Article
Costa R, Stanewsky R ( ): "When population and evolutionary genetics met behaviour." Mem Inst Oswaldo Cruz 108 (1), | Abstract | Full Article
Gentile C, Sehadova H, Simoni A, Chen C, Stanewsky R ( ): "Cryptochrome antagonizes synchronization of Drosophila's circadian clock to temperature cycles." Current Biology 23 (3), 185-195 | Abstract | Full Article
Chittka L., Jürgen Stelzer R, Stanewsky R ( ): "Daily changes in UV light levels can synchronize the circadian clock of bumblebees (Bombus terrestris)" Chronobiology International 30 (4), 434-442 | Abstract | Full Article
Szular J, Sehadova H, Gentile C, Szabo G, Chou WH, Britt SG, Stanewsky R ( ): "Cryptochrome antagonizes synchronization of Drosophila's circadian clock to temperature Rhodopsin 5- and Rhodopsin 6-mediated clock synchronization in Drosophila melanogaster is independent of retinal phospholipase C-β signaling." J Biol Rhythms 27 (1), 25-36 | Abstract | Full Article
Chen KF, Peschel N, Zavodska R, Sehadova H, Stanewsky R ( ): "QUASIMODO, a Novel GPI-anchored zona pellucida protein involved in light input to the Drosophila circadian clock" Current Biology 21 (9), 719–729 | Abstract | Full Article
Jürgen Stelzer R, Stanewsky R, Chittka L. ( ): "Circadian foraging rhythms of bumblebees monitored by radio-frequency identification" J Biol Rhythms 24 (4), 257-267 | Abstract | Full Article
Sehadova H, Glaser FT, Gentile C, Simoni A, Giesecke A, Albert JT, Stanewsky R ( ): "Temperature entrainment of Drosophila's circadian clock involves the gene nocte and signaling from peripheral sensory tissues to the brain" Neuron 64 (2), 251-266 | Abstract | Full Article
Mullineaux CW, Stanewsky R ( ): "The rolex and the hourglass: a simplified circadian clock in prochlorococcus?" J Bacteriol 191 (17), 5333-5335 | Abstract | Full Article
Yoshii T, Wülbeck C, Sehadova H, Veleri S, Bichler D, Stanewsky R, Helfrich-Förster C ( ): "The neuropeptide pigment-dispersing factor adjusts period and phase of Drosophila's clock" J Neurosci. 29 (8), | Abstract | Full Article
Landskron J, Chen KF, Wolf E, Stanewsky R ( ): "A role for the PERIOD:PERIOD homodimer in the Drosophila circadian clock" PLoS Biology 7 (4), | Abstract | Full Article
Peschel N, Chen KF, Szabo G, Stanewsky R ( ): "Light-dependent interactions between the Drosophila circadian clock factors cryptochrome, jetlag, and timeless" Current Biology 19 (3), 241-247 | Abstract | Full Article
Hodge JJ, Stanewsky R ( ): "Function of the Shaw potassium channel within the Drosophila circadian clock." PLoS One 3 (5), | Abstract | Full Article
Yoshii T, Todo T, Wülbeck C, Stanewsky R ( ): "Cryptochrome is present in the compound eyes and a subset of Drosophila's clock neurons" J Comparative Neurology 508 (6), 952-966 | Abstract | Full Article
Glaser FT, Stanewsky R ( ): "Function of the Shaw potassium channel within the Drosophila circadian clock" Cold Spring Harb Symp Quant Biol 72 233-242 | Abstract | Full Article
Sandrelli F, Tauber E, Pegoraro M, Mazzotta G, Cisotto P, Landskron J, Stanewsky R, Piccin A, Rosato E, Zordan M, Costa R, Kyriacou CP ( ): "A molecular basis for natural selection at the timeless locus in Drosophila melanogaster" Science 316 (5833), 1898-1900 | Abstract | Full Article
Veleri S, Rieger D, Helfrich-Förster C, Stanewsky R ( ): "Hofbauer-Buchner eyelet affects circadian photosensitivity and coordinates TIM and PER expression in Drosophila clock neurons" Journal of Biological Rhythms 22 (1), 29-42 | Abstract | Full Article
Collins B, Mazzoni EO, Stanewsky R, Blau J ( ): "Drosophila CRYPTOCHROME is a circadian transcriptional repressor." Current Biology 16 (5), 441-449 | Abstract | Full Article
Glaser FT, Stanewsky R ( ): "Temperature synchronization of the Drosophila circadian clock" Current Biology 15 (15), 1352–1363 | Abstract | Full Article
Wülbeck C, Szabo G, Shafer OT, Helfrich-Förster C, Stanewsky R ( ): "The novel Drosophila tim(blind) mutation affects behavioral rhythms but not periodic eclosion" Genetics 169 (2), 751-766 | Abstract | Full Article
Veleri S, Brandes C, Helfrich-Förster C, Hall JC, Stanewsky R ( ): "A self-sustaining, light-entrainable circadian oscillator in the Drosophila brain" Current Biology 13 (20), 1758–1767 | Abstract | Full Article
Rieger D, Stanewsky R, Helfrich-Förster C ( ): "Cryptochrome, compound eyes, Hofbauer-Buchner eyelets, and ocelli play different roles in the entrainment and masking pathway of the locomotor activity rhythm in the fruit fly Drosophila melanogaster" J Biol Rhythms 18 (5), 377-391 | Abstract | Full Article
Stanewsky R ( ): "Genetic analysis of the circadian system in Drosophila melanogaster and mammals" J Neurobiol 54 (1), 111-147 | Abstract | Full Article
Helfrich-Förster C, Edwards T, Yasuyama K, Wisotzki B, Schneuwly S, Stanewsky R, Meinertzhagen IA, Hofbauer A ( ): "The extraretinal eyelet of Drosophila: development, ultrastructure, and putative circadian function" J Neurosci. 22 (21), 9255-9266 | Abstract | Full Article
Stanewsky R, Lynch KS, Brandes C, Hall JC ( ): "Mapping of elements involved in regulating normal temporal period and timeless RNA expression patterns in Drosophila melanogaster" J Biol Rhythms 17 (4), 293-306 | Abstract | Full Article
Beaver LM, Gvakharia BO, Vollintine TS, Hege DM, Stanewsky R, Giebultowicz JM ( ): "Loss of circadian clock function decreases reproductive fitness in males of Drosophila melanogaster" PNAS 99 (4), 2134-2139 | Abstract | Full Article
Stempfl T, Vogel M, Szabo G, Wülbeck C, Liu J, Hall JC, Stanewsky R ( ): "Identification of circadian-clock-regulated enhancers and genes of Drosophila melanogaster by transposon mobilization and luciferase reporting of cyclical gene expression." Genetics 160 (2), 571-593 | Abstract | Full Article
Stanewsky R ( ): "Clock mechanisms in Drosophila" Cell Tissue Res 309 (1), 11–26 | Abstract | Full Article
Ivanchenko M, Stanewsky R, Giebultowicz JM ( ): "Circadian photoreception in Drosophila: Functions of cryptochrome in peripheral and central clocks." Journal of Biological Rhythms 16 (3), 205-215 | Abstract | Full Article
Helfrich-Förster C, Winter C, Hofbauer A, Hall JC, Stanewsky R ( ): "The circadian clock of fruit flies is blind after elimination of all known photoreceptors." Neuron 30 (1), 249-261 | Abstract | Full Article
Emery P, Stanewsky R, Helfrich-Förster C, Emery-Le M, Hall JC, Rosbash M ( ): "Drosophila CRY is a deep brain circadian photoreceptor" Neuron 26 (2), 493-504 | Abstract | Full Article
Emery P, Stanewsky R, Hall JC, Rosbash M ( ): "A unique circadian rhythm photoreceptor" Nature 404 456-457 | Abstract | Full Article
Giebultowicz JM, Stanewsky R, Hall JC, Hege DM ( ): "Transplanted Drosophila excretory tubules maintain circadian clock cycling out of phase with the host." Current Biology 10 (2), 107-110 | Abstract | Full Article
Reim I, Stanewsky R, Saumweber H ( ): "The puff-specific RRM protein NonA is a single-stranded nucleic acid binding protein" Chromosoma 108 (3), 162-172 | Abstract
Stanewsky R, Kaneko M, Emery P, Beretta B, Wager-Smith K, Kay SA, Rosbash M, Hall JC ( ): "The cryb mutation identifies cryptochrome as a circadian photoreceptor in Drosophila" Cell 95 (5), 681-692 | Abstract | Full Article
Stanewsky R, Jamison CF, Plautz JD, Kay SA, Hall JC ( ): "Multiple circadian-regulated elements contribute to cycling period gene expression in Drosophila" EMBO J 16 (16), 5006-5018 | Abstract | Full Article
Hege DM, Stanewsky R, Hall JC, Giebultowicz JM ( ): "Rhythmic expression of a PER-reporter in the Malpighian Tubules of decapitated Drosophila: evidence for a brain-independent circadian clock." J Biol Rhythms 12 (4), 300-308 | Abstract | Full Article
Plautz JD, Straume M, Stanewsky R, Jamison CF, Brandes C, Dowse HB, Hall JC, Kay SA ( ): "Quantitative analysis of Drosophila period gene transcription in living animals" J Biol Rhythms 12 (3), 204-217 | Abstract | Full Article
Dembinska ME, Stanewsky R, Hall JC, Rosbash M ( ): "Circadian cycling of a period-lacZ fusion protein in Drosophila: evidence for cyclical degradation." J Biol Rhythms 12 (2), 157-172 | Abstract | Full Article
Stanewsky R, Frisch B, Brandes C, Hamblen-Coyle MJ, Rosbash M, Hall JC ( ): "Temporal and spatial expression patterns of transgenes containing increasing amounts of the Drosophila clock gene period and a lacZ reporter: mapping elements of the PER protein involved in circadian cycling." J Neurosci. 17 (2), 676-696 | Abstract
Stanewsky R, Fry TA, Reim I, Saumweber H, Hall JC ( ): "Bioassaying putative RNA-binding motifs in a protein encoded by a gene that influences courtship and visually mediated behavior in Drosophila: in vitro mutagenesis of nonA." Genetics 143 (1), 259-275 | Abstract | Full Article
Brandes C, Plautz JD, Stanewsky R, Jamison CF, Straume M, Wood KV, Kay SA, Hall JC ( ): "Novel features of Drosophila period transcription revealed by real-time Luciferase reporting." Neuron 16 (4), 687-692 | Abstract | Full Article
Stanewsky R, Rendahl KG , Dill M, Saumweber H ( ): "Genetic and molecular analysis of the X chromosomal region 14B17-14C4 in Drosophila melanogaster: loss of function in NONA, a nuclear protein common to many cell types, results in specific physiological and behavioral defects." Genetics 135 (2), 419-442 | Abstract | Full Article
von Besser H., Schnabel P., Wieland C., Fritz E., Stanewsky R., Saumweber H. ( ): "The puff-specific Drosophila Protein Bj6, encoded by the gene no-on-transient A, shows homology to RNA-binding proteins." Chromosoma 100 (1), 37-47 | Abstract | Full Article
Peschel N, Veleri S, Stanewsky R "Veela defines a molecular link between Cryptochrome and Timeless in the light-input pathway to Drosophila's circadian clock " PNAS 103 (46), 17313–17318 | Abstract | Full Article
Stanewsky R "Analysis of rhythmic gene expression in adult Drosophila using the firefly luciferase reporter gene" Methods in Molecular Biology 362 131-142 | Abstract | Full Article